Kinetics of Proinsulin Conversion in Human Islets
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چکیده
منابع مشابه
Kinetics of proinsulin conversion in human islets.
Islets isolated from human cadaver pancreas were pulse-labeled (10 min with [3H]leucine) and then incubated for a 180-min chase. Islets and chase medium were collected every 15 min and analyzed by reversed-phase HPLC to quantify the percentage of radioactively labeled proinsulin, conversion intermediates, and fully processed insulin. Release of proinsulin-related labeled products into the chase...
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ژورنال
عنوان ژورنال: Diabetes
سال: 1993
ISSN: 0012-1797,1939-327X
DOI: 10.2337/diab.42.6.933